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Effect of Thymine and Cytosine Nucleobase Sequence on the Two-Dimensional Condensation of Pyrimidine Oligodeoxynucleotides at Mercury Surface
Hasoň, Stanislav ; Fojta, Miroslav
The aim of this contribution is study the effect of thymine and cytosine nucleobase composition (different lengths and/or repeat segments of either thymine or cytosine units or their combinations) within a set of the oligodeoxynucleotide (ODN) chains on the two-dimensional of homo- and hetero-pyrimidine ODNs at mercury electrode surface. It was shown that pyrimidine ODNs containing eight and more pyrimidine nucleobases can form, at negatively charged Hg surface (around1.32 V vs. Ag/AgCl), two different 2D condensed films characterized by the differential capacitances of about 9.4 (I-2D) and 7.6 mu F cm(-2) (II2D) respectively.

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